Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
发明人:
Willner, Itamar,Zhanxia, Zhang,Balogh, Dora
申请号：
HRP20171674
公开号：
HRP20171674T1
申请日:
2017.11.02
申请国别(地区):
HR
年份:
2018
代理人:
摘要：
The present invention relates to a porous substrate comprising at least one active agent entrapped within said pores of said substrate； wherein said pores are capped by at least one nucleic acid sequence； said agent is being released by a triggered reaction of said capping sequence with at least one analyte (biomarker) thereby allowing said capping to be cleaved from said pore. The invention further relates to methods of manufacturing said substrate, uses thereof for the controlled administration of active agents and diagnostic of conditions in a patient.
