Mei-Ling Ho,Je-Ken Chang,Rajalakshmanan Eswaramoorthy,Shun-Cheng Wu,Yao-Hsien Wang
申请号:
US14614718
公开号:
US20150157762A1
申请日:
2015.02.05
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method for bone regeneration which comprises administering a short term release composition into a bone area of a subject in need thereof, wherein the composition comprises a poly(lactic-co-glycolic acid) cross-linked alendronate (PLGA-ALN), wherein the composition releases the alendronate into the bone area, wherein the bone tissue of the bone area is exposed in situ to a therapeutically effective amount of the alendronate over 9 days.