Germaine Fuh;Frederic A. Fellouse;Christian Wiesmann;Hans-Peter Gerber;Wei-Ching Liang;Sachdev S. Sidhu
发明人:
Germaine Fuh,Hans-Peter Gerber,Wei-Ching Liang,Frederic A. Fellouse,Sachdev S. Sidhu,Christian Wiesmann
申请号：
US12844616
公开号：
US08101177B2
申请日:
2010.07.27
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naive libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the antibodies in research, diagnostic and therapeutic applications.
