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METHODS FOR STERILIZING MATERIALS CONTAINING BIOLOGICALLY ACTIVE AGENTS
专利权人:
ALEXANDER M. HARMON
发明人:
ALEXANDER M. HARMON,LAURA J. BROWN,CHARLES J. BUCKLE,FREDERICK HALPERIN,STANKO BODNAR
申请号:
US13492175
公开号:
US20120315698A1
申请日:
2012.06.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Provided are methods for sterilizing a material comprising a biologically-active agent comprising irradiating said material with ionizing radiation at a dose of about 5 kGy to about 25 kGy while maintaining said material in an atmosphere comprising at least 95% by volume inert gas and at a temperature of about 4° C. or lower. Also provided are sterilized materials comprising a biologically-active agent, wherein said materials exhibit substantially the same amount of biological activity as a non-sterilized control.
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