Alexander M. Harmon,Laura J. Brown,Charles J. Buckle,Frederick Halperin,Stanko Bodnar
申请号：
US12337425
公开号：
US08236538B2
申请日:
2008.12.17
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Provided are methods for sterilizing a material comprising a biologically-active agent comprising irradiating said material with ionizing radiation at a dose of about 5 kGy to about 25 kGy while maintaining said material in an atmosphere comprising at least 95% by volume inert gas and at a temperature of about 4° C. or lower. Also provided are sterilized materials comprising a biologically-active agent, wherein said materials exhibit substantially the same amount of biological activity as a non-sterilized control.
