Compositions and methods are provided for prophylactic or therapeutictreatment of a mammal for hearing or balanceimpairments involving neuronal damage, loss, or degeneration, byadministration of a therapeutically effective amount of aredox- active therapeutic. Also provided are improved compositions and methodsfor treatments requiring administration of apharmaceutical having an ototoxic side-effect in combination with atherapeutically effective amount of a redox-active therapeuticto treat the ototoxicity.
