GUO ZHU ZHENG,JOHN WANG,SUDEEP PRAJAPATI,GREGG F. KEANEY,BAUDOUIN GERARD,KENZO ARAI,XIANG LIU,KAZUNOBU KIRA,PARCHAREE TIVITMAHAISOON,NICHOLAS C. GEARHART,YOSHIHIKO KOTAKE,SATOSHI NAGAO,REGINA KANADA S
申请号：
PT15727125
公开号：
PT3143016T
申请日:
2015.05.13
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
The present invention provides novel pladienolide pyridine compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancer, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful.
