PROBLEM TO BE SOLVED: To provide a novel integrase inhibitor.SOLUTION: There is provided the integrase inhibitor to a composition which is expressed by a formula (I): (in the formula, RC and RD form a ring together with mutually-adjacent carbon atoms, and the ring may be a shrunk ring. Y is hydroxy, mercapto or amino Z is an oxygen atom, a sulfur atom or NH) and RA is a group or the like expressed by the following formula (I-1) (in the formula, a C-ring is a nitrogen-containing aromatic heterocycle.).COPYRIGHT: (C)2013,JPO&INPIT【課題】インテグラーゼ阻害剤の提供。【解決手段】式(I):(式中、RC及びRDは一緒になって隣接する炭素原子と共に環を形成し、該環は縮合環であってもよい。Yはヒドロキシ、メルカプト又はアミノであり;Zは酸素原子、硫黄原子又はNHであり;RAは下式:(式中、C環は含窒素芳香族複素環)で示される基等)で示される化合物にインテグラーゼ阻害剤。【選択図】なし