CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO)
发明人:
PASTOR FERNÁNDEZ, JOAQUIN,OYARZABAL SANTAMARINA, JULEN,SALUSTE, CARL-GUSTAF, PIERRE,BLANCO APARICIO, CARMEN,ALVAREZ ESCOBAR, ROSA, MARÍA,RIVERO BUCETA, VIRGINIA
申请号：
SG2012060943
公开号：
SG183361A1
申请日:
2011.02.18
申请国别(地区):
SG
年份:
2012
代理人:
摘要：
There is provided compounds of formula (I), wherein R1, R2, R3 and R4 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PIM family kinase, such as PIM-1, PIM-2 and/or PIM-3, and/or Flt3) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.
