Rosa Maria Alvarez Escobar;Carmen Blanco Aparicio;Julen Oyarzabal Santamarina;Joaquin Pastor Fernández;Carl-Gustaf Pierre Saluste;Virginia Rivero Buceta
发明人:
Joaquin Pastor Fernández,Julen Oyarzabal Santamarina,Carl-Gustaf Pierre Saluste,Carmen Blanco Aparicio,Rosa Maria Alvarez Escobar,Virginia Rivero Buceta
申请号：
US13579781
公开号：
US20130065883A1
申请日:
2011.02.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
There is provided compounds of formula (I), wherein R1, R2, R3 and R4 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PIM family kinase, such as PIM-1, PIM-2 and/or PIM-3, and/or Flt3) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.
