組織損傷修復中的基質細胞衍生因子1的蛋白酶抗性突變體

• 收藏
• 分享

专利权人:

THE BRIGHAM AND WOMENS HOSPITAL INC.

发明人:

RICHARD T. LEE,VINCENT SEGERS

申请号：

HK10103057.2

公开号：

HK1136211B

申请日:

2010.03.23

申请国别(地区):

HK

年份:

2015

代理人:

摘要：

The present invention is directed stromal cell derived factor-1 peptides that have been mutated to make them resistant to digestion by the proteases dipeptidyl peptidase IV (DPPIV) and matrix metalloproteinase-2 (MMP-2) but which maintain the ability of native SDF-1 to attract T cells. The mutants may be attached to membranes formed by self-assembling peptides and then implanted at sites of tissue damage to help promote repair.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/