Wang, Feng,Tremblay, Matthew S.,Young, Travis,Alvarez, Nicole,Liu, Yan,Du, Juanjuan,Schultz, Peter G.
申请号:
AU2016315889
公开号:
AU2016315889A1
申请日:
2016.09.02
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Disclosed herein are immunoglobulin fusion proteins comprising an insulin therapeutic peptide and an immunoglobulin region that targets the insulin therapeutic peptide to the liver of an individual in need thereof. Further disclosed herein are compositions comprising the immunoglobulin fusion proteins and methods for using the immunoglobulin fusion proteins for the treatment or prevention of a disease or condition in a subject, for example, diabetes and diabetes related conditions.