An image pickup apparatus includes: an image pickup device in which a high-sensitivity pixel group and a normal sensitivity pixel group are arranged； a control section configured to read the high-sensitivity pixel group alone to form a first frame signal for which a configuration of the first pixel group to be read according to a control signal synchronized with a light source selection control signal for selecting a type of illuminating light from a light source capable of emitting a plurality of types of illuminating light for illuminating an object, read all pixels including the high-sensitivity pixel group and the normal sensitivity pixel group to form a second frame signal and alternately output the first and second frame signals； and a frame addition circuit configured to perform frame addition processing of the first and second frame signals to output an image signal for one frame.
