ZHOU JOE,SUN JIURU,ZHAO JIANYANG,WANG JUN,WANG SHAOXIONG,MA XINXING,LIN JUN
申请号：
IN1966/MUMNP/2011
公开号：
IN2011MN01966A
申请日:
2011.09.20
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
Provided are anti-angiogenic fusion proteins comprising Ig-like domain fragments of VEGF receptor and multimerizing components such as Fc domain of IgG, which have excellent capacity for binding VEGF and PIGF, and can be used for inhibiting angiogenesis, preventing and treating VEGF related diseases or suppressing tumor. The fusion proteins have good stability, long half-life and are capable of binding multivalently to VEGF molecules.
