System of the present invention close what provide it is a kind of have the function of that Parakeratosis inhibitions, hair pore shrinkage, pachylosis prevent what improved etc. Parakeratosis inhibitor, hair pore shrinkage agent, pachylosis from preventing improver, external preparation for skin constituent of the one kind with aforementioned function is more provided.System of the present invention provides a kind of Parakeratosis inhibitor, hair pore shrinkage agent, and characteristic stretches the compound institute winner of the salt institute of methylene imine carboxylic acid derivates, β-alanine derivatives and each derivative in groups selected from glycine derivative, amido dicarboxylic acid derivatives, anilide amido dicarboxylic acid derivatives, pyrrolidine carboxylic acid derivatives, piperidine carboxylic acid derivative, six to be one kind or two or more. Also, provide it is a kind of containing it is one kind or two or more selected from specific glycine derivative and its salt, with specific amido sulfate derivative and its salt compound in groups external preparation for skin constituent.本發明係關於提供一種具有不全角化症抑制、毛孔縮小、皮膚粗糙防止．改善等之功能之不全角化症抑制劑、毛孔縮小劑、皮膚粗糙防止．改善劑，更提供一種具有前述功能之皮膚外用組成物。本發明係提供一種不全角化症抑制劑、毛孔縮小劑，其特徵為1種或2種以上選自甘胺酸衍生物、胺基二羧酸衍生物、醯基胺基二羧酸衍生物、吡咯烷羧酸衍生物、哌啶羧酸衍生物、六伸甲基亞胺羧酸衍生物、β-丙胺酸衍生物、及該各衍生物的鹽所成群之化合物所成者。又，提供一種含有1種或2種以上選自特定甘胺酸衍生物及其鹽、與特定胺基硫酸衍生物及其鹽所成群之化合物的皮膚外用組成物。
