HUANG, TAISHENG,黄台生,黃台生,FENG, HAO,冯皓,馮皓,KONG, LINGQUAN,孔玲坤,孔玲坤,WANG, ANLAI,王安来,王安來,YE, HAI FEN,叶海芬,葉海芬
申请号：
TW101137845
公开号：
TW201321371A
申请日:
2012.10.12
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The present invention provides isoindolinone and pyrrolopyridinone derivatives, as well as their compositions and methods of use, that inhibit the activity of the serine/threonine kinase, Akt, and are useful in the treatment of diseases related to the activity of Akt including, for example, cancer and other diseases.本發明提供抑制絲胺酸/蘇胺酸激酶Akt之活性且適用於治療與Akt之活性相關之疾病,包括例如癌症及其他疾病的異吲哚啉酮及吡咯并吡啶酮衍生物以及其組合物及使用方法。
