A method of sustainably producing an aquaculture meat product by feeding a fish over its dietary cycles a sustainably produced aquaculture feed composition is disclosed. This method comprises: a) formulating an aquaculture feed composition by replacing all or part of fish oil in the composition with an alternate source(s) of eicosapentaenoic acid ("EPA") and, optionally, docosahexaenoic acid ("DHA"), wherein the EPA:DHA ratio is at least 2:1 in the aquaculture feed composition and, b) adjusting the aquaculture feed composition over the life cycle of the fish to produce an aquaculture meat product wherein the Feeder Fish Efficiency Ratio for fish oil is equal to or less than two and the aquaculture meat product has a EPA:DHA ratio equal to or greater than 1.4:1.