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NOUVEAU DERIVE 1,2,3,4-TETRAHYDROQUINOXALINE AYANT UNE ACTIVITE DE LIAISON A UN RECEPTEUR DE GLUCOCORTICOIDE
专利权人:
SANTEN PHARMACEUTICAL CO.; LTD.
发明人:
MATSUDA, MAMORU,MORI, TOSHIYUKI,KAWASHIMA, KENJI,YAMAMOTO, MINORU,KATO, MASATOMO,TAKAI, MIWA,NAGATSUKA, MASATO,KOBAYASHI, SACHIKO
申请号:
CA2643070
公开号:
CA2643070C
申请日:
2007.03.14
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
An object of the present invention is to synthesize anovel 1,2,3,4-tetrahydroquinoxaline derivativerepresented by formula (1) and to find apharmacological action of the derivative. In theformula, the R1 represents a halogen, an alkyl,cycloalkyl, aryl or heterocyclic group, or the like;p represents 0 to 5; R2 represents a halogen, analkyl, hydroxyl or alkoxy group, or the like; qrepresents 0 to 2; R3 represents hydrogen, an alkyl,alkenyl, alkylcarbonyl or arylcarbonyl group, or thelike; R4 and R5 independently represent hydrogen, ahalogen, an alkyl, alkenyl, alkynyl, cycloalkyl, arylor heterocyclic group, or the like; R6 representshydrogen, an alkyl, alkenyl, alkynyl, cycloalkyl,aryl or heterocyclic group, or the like; A representsan alkylene; R7 represents OR8, NR8R9, SR8, S(O)R8,S(O)2R8; and X represents O or S.(see formula 1)
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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