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DERIVE 5-PHENYLAZAINDOLE POSSEDANT UN EFFET D'ACTIVATION DE L'AMPK
专利权人:
LTD.;SHIONOGI & CO.
发明人:
TAMURA, YUUSUKE,OZASA, HIROKI
申请号:
CA3014858
公开号:
CA3014858A1
申请日:
2017.02.24
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Provided is a compound useful as an AMPK activator. The compound is one that is represented by formula: (in the formula, X represents a substituted or unsubstituted monocyclic heterocyclyl, etc., ring A is a substituted aryl, a substituted heteroaryl, a substituted cycloalkyl, a substituted cycloalkenyl, or a substituted heterocyclyl, ring A may further have a substituent in addition to Y, Y- represents a halogen, hydroxy, cyano, nitro, carboxy, a substituted or unsubstituted alkyl, a substituted or unsubstituted alkenyl, a substituted or unsubstituted alkynyl, etc., R4, R5, R6, and R7 each independently represent hydrogen, a halogen, hydroxy, cyano, nitro, carboxy, a substituted or unsubstituted alkyl, a substituted or unsubstituted alkenyl, a substituted or unsubstituted alkynyl, a substituted or unsubstituted alkyloxy, a substituted or unsubstituted alkylthio, a substituted or unsubstituted alkylsulfonyl, a substituted or unsubstituted acyl, substituted or unsubstituted carbamoyl, substituted or unsubstituted sulfamoyl, or substituted or unsubstituted amino, R8 represents hydrogen, a halogen, hydroxy, cyano, nitro, carboxy, a substituted or unsubstituted alkyl, a substituted or unsubstituted alkenyl, a substituted or unsubstituted alkynyl, etc., and R9 represents hydrogen, a halogen, hydroxy, cyano, nitro, carboxy, a substituted or unsubstituted alkyl, a substituted or unsubstituted alkenyl, a substituted or unsubstituted alkynyl, etc.), or a pharmaceutically acceptable salt thereof.
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