compositions and processes for the production of immunoglobulins. The present invention relates to oligonucleotides for the isolation of human antibody cdnas from cells or cell lines, such as hybridomas. The invention further provides cdnas encoding at least one cdr provided from a heavy or light chain of a human monoclonal antibody that binds to the protective antigen of b. anthracis； and cdnas encoding at least one cdr provided from a heavy or light chain of a human monoclonal antibody that binds to the lethal factor of b. anthracis. The invention further provides expression vectors containing one or more isolated DNAs according to the processes of the invention, host cells expressing one or more DNAs of the invention, and transgenic plants and animals expressing one or more DNAs. In certain embodiments of the invention, the expression system is a plant-based expression system. The invention further provides antibody compositions comprising one or more antibodies produced by expression of an isolated cdna according to the processes of the invention in a suitable expression system. Further encompassed by the invention are kits containing one or more of the compositions provided, as well as processes for producing and using the compositions provided.composições e processos para a produção de imunoglobulinas. a presente invenção refere-se a oligonucleotídeos para o isolamento de cdnas de anticorpos humanos partindo de células ou linhagens de células, tais como hibridomas. a invenção fornece ainda cdnas que codificam pelo menos uma cdr fornecida de uma cadeia pesada ou de uma cadeia leve de um anticorpo monoclonal humano que se liga ao antígeno protetor de b. anthracis； e cdnas que codificam pelo menos uma cdr fornecida de uma cadeia pesada ou de uma cadeia leve de um anticorpo monoclonal humano que se liga ao fator letal de b. anthracis. a invenção fornece ainda vetores de expressão que contêm um ou mais cdnas isolados de acordo com os processos da invenção, células
