Dérivés d'acide acétique carbamoylmethylamino substitués en tant que nouveaux inhibiteurs NEP

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专利权人:

Novartis AG

发明人:

申请号：

EP14155848.6

公开号：

EP2735561A1

申请日:

2010.11.18

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention provides a compound of formula I；or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1, A2, X1, sand m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

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