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Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors
专利权人:
Toshio Kawanami;Yuki Iwaki;Gary Michael Ksander;Muneto Moji
发明人:
Yuki Iwaki,Toshio Kawanami,Gary Michael Ksander,Muneto Moji
申请号:
US14093956
公开号:
US08877786B2
申请日:
2013.12.02
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a compound of formula I;or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1, A2, X1, s and m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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