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Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors
专利权人:
Toshio KAWANAMI;Muneto MOGI;Yuki IWAKI;Gary Michael KSANDER
发明人:
Yuki IWAKI,Toshio KAWANAMI,Gary Michael KSANDER,Muneto MOGI
申请号:
US13449357
公开号:
US20120202862A1
申请日:
2012.04.18
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a compound of formula I;or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1, A2, X1, s and m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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