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OLIGONUCLÉOTIDES POUR INTERFÉRENCE ARN ET APPLICATIONS BIOLOGIQUES ASSOCIÉES
专利权人:
POLYPLUS TRANSFECTION
发明人:
申请号:
EP06754634.1
公开号:
EP1888749B1
申请日:
2006.06.01
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The invention relates to compositions comprising double-stranded oligonucleotides of identical or different sequences and/or length, said oligonucleotides having sequences 3′N1N2 . . . Ni-1Ni . . . Nj5′ wherein—3′Ni . . . Nj5′ is half of a double-stranded 19-28mer oligonucleotide of sequence complementary to a target nucleic acid sequence present in a living cell, and—3′N1 . . . Ni-15′ is a 3-50mer overhang of sequence allowing oligomerization of said double-stranded oligonucleotide. Compositions of transfection comprising said oligonucleotide compositions and there used for therapeutical application.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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