Single-chain circular rna, method of producing the same and pharmaceutical compositions comprising it

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专利权人:

RIKEN

发明人:

申请号：

IL20197509

公开号：

IL201975A

申请日:

2009.11.05

申请国别(地区):

IL

年份:

2013

代理人:

摘要：

The present invention relates to a single-chain circular RNA having a sustained or slow-releasing RNA interference effect, characterized in that the single-chain circular RNA comprises a sense strand sequence, an antisense strand sequence complementary to the sense strand sequence, identical or different two loop sequences between the sense strand and the antisense strand, connecting both strands, wherein the sense strand and the antisense strand are paired to form a stem.

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