A tissue anomaly detection apparatus (1000), comprising: a patient positioning structure (1) configured to allow the patient assuming a detection position a probe antenna device (2) structured to radiate incident radio-frequency signal to irradiate a patient tissue in near-field conditions so as to produce a first resulting radio-frequency signal (SBS). The detection apparatus is characterised in that it further includes: a reflector (3) positioned so as to reflect at least part of the incident radio-frequency signal which has not irradiated the patient tissue and generate a reflected signal (SR), a receiving device (4) structured to receive the first resulting signal and the reflected signal and provide corresponding received data, a processing module (5) structured to process the received data to provide an information indicating detection of an anomaly in said tissue.