PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for the oral cavity, xerostomia improving agent, and xerostomia-preventive agent which have an excellent effect for improving and preventing xerostomia and high safety, and to provide an aquaporin production promoter which has the excellent aquaporin production promoter action and has high safety.SOLUTION: There are provided a pharmaceutical composition for oral cavities which contains a pineapple ceramide, a xerostomia improving agent which contains the pineapple ceramide, a xerostomia-preventive agent which contains the pineapple ceramide, and an aquaporin production promoter which contains the pineapple ceramide.COPYRIGHT: (C)2014,JPO&INPIT【課題】優れた口腔乾燥症改善、予防効果を有し、安全性の高い口腔用医薬組成物、口腔乾燥症改善剤、及び口腔乾燥症予防剤、並びに優れたアクアポリン産生促進作用を有し、安全性の高いアクアポリン産生促進剤の提供。【解決手段】パイナップルセラミドを含有する口腔用医薬組成物、パイナップルセラミドを含有する口腔乾燥症改善剤、パイナップルセラミドを含有する口腔乾燥症予防剤、及びパイナップルセラミドを含有するアクアポリン産生促進剤である。【選択図】図3C
