The joint stabilization device (1), particularly for the patellofemoral joint, comprises: support means (2a, 2b) positionable at the patellar portion (3) of a leg (4) of a patient (5); a sustaining element (7) of elongated shape, having a first extremity (8) and a second extremity (9) opposite to each other, associated with the support means (2a, 2b) and positionable laterally to the patella (6) of the patient (5); a first traction element (14) and a second traction element (15) associated with the first extremity (8) and with the second extremity (9), respectively; a first directing element (16) and a second directing element (17) which are associated with the sustaining element (7) and interposed between the first extremity (8) and the first traction element (14) and between the second extremity (9) and the second traction element (15) respectively, wherein the first traction element (14) and the second traction element (15) are adapted to position the sustaining element (7) in a predefined position, the first directing element (16) and the second directing element (17) being adjustable depending on the predefined position.