Benzenesulfonamide upregulators of NPC1 for neimann-pick disease and other lysosomal storage disorders

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专利权人:

Icahn School of Medicine at Mount Sinai;National Institutes of Health

发明人:

Chen, Fannie,Ioannou, Yiannis,Patnaik, Samarjit,Taylor, Mercedes,Calvo, Raul Rolando,Marugan, Juan Jose,Southall, Noel,Zheng, Wei,Ferrer-Alegre, Marc,Dehdasthi, Seameen,Dranchak, Patricia

申请号：

AU2016219231

公开号：

AU2016219231A2

申请日:

2016.02.11

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

Methods and compositions for treating lysosomal storage disorders are disclosed. The methods involve administering a genus of benzenesulfonamides, particularly N-[3-(aminosulfonyl)phenyl]-benzamides and heteroarylamides. A genus of suitable compounds is shown in formula I:

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