It include one or more compounds the present invention relates to biological response modifiers (BRM), with for enhancing immune system and BRMs of the invention includes the prevention or treatment for expanding specific immune response, as the vaccine of adjuvant, or when and pathogenic antigens, and enhancing immune system it is usual. Present invention is equally related to reduce without constraint or unsuitable inflammatory response and/or immune response, such as treatment or prevention autoimmune disease and illness and related symptoms. Moreover, it relates to which manufacturing BRM compounds includes isolation serum from mammal, serum chromatographs slipstream and molecular cut off is dialysed, obtains the patient that one or more purifying BRM compounds are suitable for giving needs.
