MOSS, STEVEN JAMES,GREGORY, MATTHEW ALAN,WILKINSON, BARRIE
申请号：
ES12716539
公开号：
ES2533438T3
申请日:
2012.03.29
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
Compound of formula (I): ** Formula ** in which: the remainder X1 represents -OR1, -NR1R2 or R3； R1, R2 and R3 independently represent alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkylcycloalkyl, alkylcycloalkenyl, alkenylcycloalkyl, alkenylcycloalkenyl, aryl, heteroaryl, alkylaryl, alkylheteroaryl, alkenyl or alkenylhenyl heteroaryl mono-heteroaryl groups； and wherein one or more carbon atoms of R1, R2 and R3 that are not part of an aryl or heteroaryl group are optionally replaced by a heteroatom selected from O, N and S (O) p in which p represents 0, 1 or 2 and wherein one or more carbon atoms of R1, R2 and R3 are optionally replaced by carbonyl； or R1 and R2 are attached such that NR1R2 represents a saturated or unsaturated heterocyclic ring containing the specified nitrogen atom and in which one or more carbon atoms of said ring are optionally replaced by an additional heteroatom selected from O, N and S (O) p in which p represents 0, 1 or 2 and in which one or more carbon atoms of said ring are optionally replaced by carbonyl and the heterocyclic ring may be optionally fused to an aryl or heteroaryl ring； and wherein one or more carbon atoms of a group R1, R2 and R3 may be optionally substituted with one or more halogen atoms； or R1 and / or R2 represents hydrogen； R9 represents H or OH； n represents a single or double bond, with the proviso that when n represents a double bond R9 represents H； R4, R5, R6, R7 and R8 independently represent H, F, Cl, Br, alkenyl or alkyl in which one or more carbon atoms of said alkyl group are optionally replaced by a heteroatom selected from O, N and S (O ) p in which p represents 0, 1 or 2 and in which one or more carbon atoms of said alkyl group are optionally replaced by carbonyl and the alkyl group may be optionally substituted with one or more halogen atoms； X2, X3, X4, X5 and X6 independently represent C or N, and in the event that any of these groups represents N, the attached substituent is absent； with the proviso that
