John C. Alverdy,Matthew Tirrell,Olga Y. Zaborina,Jun Mao,Wei Chen
申请号:
US16338330
公开号:
US20190247423A1
申请日:
2017.09.29
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The disclosure provides products and methods of treating diseases and disorders involving microbial pathogens, such as intestinal microbial pathogens, e.g., Pseudomonas aeruginosa, by administering an effective amount of a phosphorylated polyethylene glycol compound of defined structural organization. Those diseases and disorders characterized by an epithelium attacked by a microbial pathogen are contemplated, including gastrointestinal infections and inflammation, e.g., treatment of intestinal or esophageal anastomosis or treatment or suppression of anastomotic leakage.