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Nye kumarinderivater med antitumoraktivitet
专利权人:
Chugai Seiyaku Kabushiki Kaisha;Sakai, Toshiyuki
发明人:
Watanabe, Fumio,Ozawa, Sawako,Iikura, Hitoshi,Hyoudoh, Ikumi,Aoki, Toshihiro,Furuichi, Noriyuki,Matsushita, Masayuki,Sakaitani, Masahiro,Ho, Pil-Su,Tomii, Yasushi,Takanashi, Kenji,Harada, Naoki
申请号:
NO20083542
公开号:
NO341421B1
申请日:
2008.08.14
申请国别(地区):
NO
年份:
2017
代理人:
摘要:
The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: wherein: X is selected from heteroaryl etc., Y 1 and Y 2 are selected from -N= etc., Y 3 and Y 4 are selected from -CH= etc., A is selected from sulfamide etc., R 1 is selected from hydrogen etc., and R 2 is selected from C 1-6 alkyl etc. The compound or salt has sufficiently high antitumor activity, and is useful in the treatment of cell proliferative disorders, particularly cancers. The present invention also provides a pharmaceutical composition containing the compound or salt as an active ingredient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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