The present invention addresses the problem of providing a liposome composition and a pharmaceutical composition that exhibit a high AUC. The present invention provides: a liposome composition that contains, as constituent components of the liposome membrane, a diacylphosphatidylethanolamine modified by a hydrophilic polymer, a dihydrosphingomyelin, and cholesterols； and a pharmaceutical composition containing the liposome composition, wherein the liposome composition encapsulates a drug, an inner aqueous phase thereof contains ammonium sulfate, and the molar ratio of sulfate ions in the inner aqueous phase to the drug in the entire aqueous phase is equal to or greater than 0.36.
