PROCÉDÉ DE PRÉPARATION DE MICELLE POLYMÈRE CONTENANT UN MÉDICAMENT ANIONIQUE

• 收藏
• 分享

专利权人:

Samyang Biopharmaceuticals Corporation

发明人:

申请号：

EP16876080.9

公开号：

EP3391875A4

申请日:

2016.12.16

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Disclosed is a method for preparing a composition for an anionic drug delivery with increased production yield, comprising forming nanoparticles by using electrostatic interaction of an anionic drug and a cationic compound in an aqueous phase； and incorporating the nanoparticles into polymeric micelles comprising an amphiphilic polymer and optionally a polylactic acid salt to increase the electrostatic interaction and hydrophobic binding, thereby increasing the entrapment efficiency of the anionic drug in the formulation.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/