Karl Richard GIBSON,Alison JONES,Mark Ian KEMP,Andrew MADIN,Martin Lee STOCKLEY,Gavin Alistair WHITLOCK,Michael D WOODROW,Keith Allan MENEAR
申请号：
US16080506
公开号：
US20190010122A1
申请日:
2017.03.17
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention relates to novel compounds of formula I which are inhibitors of deubiquitylating enzymes (DUBs) and/or desumoylating enzymes. In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase 7 or ubiquitin specific peptidase 7 (USP7). The invention further relates to methods for the preparation of these compounds and to their use in the treatment of cancer.
