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AGENTS DE DEGRADATION DE PROTEINE MDM2
专利权人:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人:
WANG, SHAOMENG,LI, YANGBING,YANG, JIULING,AGUILAR, ANGELO,ZHOU, BING,HU, JIANTAO,XU, FUMING,REJ, ROHAN,HAN, XIN
申请号:
CA3020275
公开号:
CA3020275A1
申请日:
2017.04.06
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present disclosure provides compounds represented by Formula I-A: A1- L 1-B1 I-A and the pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein A1, B1, and L1 are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I-A for use to treat a condition or disorder responsive to degradation of MDM2 protein such as cancer.
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