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Substituted Fused Heteroaromatic Compounds as Kinase Inhibitors and the Use Thereof
专利权人:
IMPACT THERAPEUTICS; INC.
发明人:
Suixiong CAI,Ye Edward TIAN
申请号:
US16476762
公开号:
US20190358225A1
申请日:
2018.01.09
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The disclosure relates to substituted fused heteroaromatic compounds and the use thereof. Specifically, the disclosure provides compounds of the following Formula I:or a pharmaceutically acceptable salt or prodrug thereof, wherein A1-A4, B1-B3, D1-D4 and R1-R3 are defined herein. Compounds having Formula I are kinalse inhibitors. Therefore, compounds of the disclosure may be used to treat clinical conditions caused by DDR functional defects, such as cancer.
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