Jérôme Berger,Robert Gurny,Marianne Reist Oechslin
申请号:
US10593678
公开号:
US08835514B2
申请日:
2004.03.22
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The composition disclosed is a pseudo-thermosetting neutralized chitosan composition, neutralized with an hydroxylated base, forming a phosphate-free transparent hydrogel at a temperature higher than 5° C. Said composition contains a homogeneously reacetylated chitosan derived from a chitosan having a deacetylation degree of 80-90%, having a molecular weight of not smaller than 200 kDa and a deacetylation degree of 30-60%, and may further contain a diol. Said composition may be used as a drug delivery system.