Jérôme Berger,Robert Gurny,Marianne Reist Oechslin
申请号：
US12654700
公开号：
US08507563B2
申请日:
2009.12.29
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The composition disclosed is a pseudo-thermosetting neutralized chitosan composition, neutralized with a hydroxylated base, forming a phosphate-free transparent hydrogel at a temperature higher than 5° C. Said composition contains a homogeneously reacetylated chitosan derived from a chitosan having a deacetylation degree of 80-90%, having a molecular weight of not smaller than 200 kDa and a deacetylation degree of 30-60%, and may further contain a diol. Said composition may be used as a drug delivery system.
