The present invention relates to a novel serotonin reuptake inhibitor which also exhibits 5-HT 2 C antagonistic action (antidepressive and anxiolytic effects), in particular, 5-HT 2 C inverse agonistic action comprising Compound (1) : or a pharmaceutically acceptable salt thereof wherein R 1 , R 2 , R 3 and R 4 are independently hydrogen or C 1-6 alkyl etc.； R 5 is C 4-7 alkyl or -(CR 8 R9) r -E； R 6 , R 7 , R 8 and R 9 are independently hydrogen, fluorine or C 1-6 alkyl； A is C 6-10 aryl or heteroaryl etc.； r is 1, 2, 3 or 4； E is C 3-8 cycloalkyl or C 6-10 aryl etc.； L is oxygen, sulfur or -NR 10 -； n is 1, 2 or 3； R 10 is hydrogen or C 1-6 alkyl etc.； and X is hydrogen or halogen etc.
