Eric Dixon,Rainer Blaesius,Stephen Simkins,Steven L. Knapp,George Brough,Karen Lenz,Johannes Schweizer,Peter Lu,David Garman,Jon Silver,Charles Mahoney,Chamorro Somoza Diaz-Sarmiento
申请号：
US13265332
公开号：
US20120141502A1
申请日:
2010.04.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The subject invention provides an antibody composition for detecting E6 protein of at least one HPV strain in a sample. The subject antibodies may be used to detect oncogenic HPV E6 proteins in a sample, and the antibodies find use in a variety of diagnostic and therapeutic applications, including methods of diagnosing and treating cancer. Kits for performing the subject methods and containing the subject antibodies are also provided. Also disclosed in the present invention is a method of generating an antibody that specifically binds to amino-terminus of E6 proteins of at least two HPV strains.
