LU, PETER,GARMAN, JONATHAN,BELMARES, MICHAEL,SOMOZA DIAZ-SARMIENTO, CHAMORRO,SCHWEIZER, JOHANNES
申请号：
AT04815434
公开号：
AT554106T
申请日:
2004.12.23
申请国别(地区):
AT
年份:
2012
代理人:
摘要：
The subject invention provides antibodies, including polyclonal and monoclonal antibodies, that bind to E6 proteins from at least three oncogenic strains of HPV. In general, the antibodies bind to amino acids motifs that are conserved between the E6 proteins of different HPV strains, particularly HPV strains 16 and 18. The subject antibodies may be used to detect HPV E6 protein in a sample, and, accordingly, the antibodies find use in a variety of diagnostic applications, including methods of diagnosing cancer. Kits for performing the subject methods and containing the subject antibodies are also provided.
