DIXON ERIC P,BLAESIUS RAINER,SIMKINS STEPHEN,KNAPP STEVEN L,BROUGH GEORGE H,LENZ KAREN,SCHWEIZER JOHANNES,LU PETER,GARMAN DAVID,SILVER JON,MAHONEY CHARLES,DIAZ SARMIENTO CHAMORRO SOMOZA
申请号：
IN8501/DELNP/2011
公开号：
IN2011DN08501A
申请日:
2011.11.02
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
[00323] The subject invention provides an antibody composition for detecting E6 protein of at least one HPV strain in a sample. The subject antibodies may be used to detect oncogenic HPV E6 proteins in a sample, and the antibodies find use in a variety of diagnostic and therapeutic applications, including methods of diagnosing and treating cancer. Kits for performing the subject methods and containing the subject antibodies are also provided. Also disclosed in the present invention is a method of generating an antibody that specifically binds to amino-terminus of E6 proteins of at least two HPV strains.
