PROCESS FOR PRODUCING INTERMEDIATE PRODUCTS FOR THE MANUFACTURE OF NEW MACROCLES AS INHIBITORS OF THE PROTEASOMIC DEGRADATION OF P27 SUCH AS ARGYRINE AND DERIVATIVES THEREOF, AND USE THEREOF OF MACROCYCLES

• 收藏
• 分享

专利权人:

MEDIZINISCHE HOCHSCHULE HANNOVER;HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER

发明人:

KALESSE, MARKUS,MALEK, NISAR,FRANK, RONALD,BRODMANN, TOBIAS,BUELOW, LEILA,RENTSCH, ANDREAS,GIRBIG, ANNA-KATHARINA,EGGERT, ULRIKE

申请号：

AT09797415

公开号：

AT557032T

申请日:

2009.06.23

申请国别(地区):

AT

年份:

2012

代理人:

摘要：

The present invention relates to the use of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular argyrin and derivatives thereof, for a treatment in a variety of conditions, such as the induction of immunotolerance, autoimmune diseases, bacterial infections, and proliferative diseases, such as cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/