Method for producing intermediates for the production of novel macrocycles that are inhibitors of the proteasomic degradation of p27, such as argyrin and derivatives thereof, and uses of said macrocycles
Medizinische Hochschule Hannover;Helmholtz-Zentrum fur Infektionsforschung GmbH;Gottfried Wilhelm Leibniz Universitat Hannover
发明人:
Brodmann, Tobias,Rentsch, Andreas,Eggert, Ulrike,Malek, Nisar,Girbig, Anna-Katharina,Kalesse, Markus,Bulow, Leila,Frank, Ronald
申请号：
AU2009270571
公开号：
AU2009270571B2
申请日:
2009.06.23
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention relates to the use of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular argyrin and derivatives thereof, for a treatment in a variety of conditions, such as the induction of immunotolerance, autoimmune diseases, bacterial infections, and proliferative diseases, such as cancers.
