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経口投与用医薬用吸着剤の製造方法
专利权人:
FUTAMURA CHEMICAL CO LTD
发明人:
KUROKAWA HIROYUKI,黒川 普之,HIBI KEITA,日比 圭太,KOSAKA TSUTOMU,高阪 務,SUZUKI KEISUKE,鈴木 恵介
申请号:
JP2015196837
公开号:
JP2016014057A
申请日:
2015.10.02
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide a production method for a sorbent for oral administration medicines which is excellent in adsorption capacity and selective adsorption properties of a toxin to be eliminated in spite of a small dose, and in which an economical and environmental load are reduced.SOLUTION: In production of a spherical activated carbon with an average pore diameter of 1.5 to 2.2 nm, a BET specific surface area of 700 to 3000 m2/g, an average particle diameter of 100 to 1100 μm, the amount of surface oxide of 0.05 meq/g or more, and a packing density of 0.4 to 0.8 g/mL, a viscose solution is introduced into an acid coagulation bath, regeneration to a cellulose is facilitated through solidification of the viscose solution, a spherical regenerated cellulose is obtained in the coagulation bath, the spherical regenerated cellulose is carbonized at 300 to 700°C under a nitrogen atmosphere, steam activation is performed at 750 to 1000°C, acid cleaning is performed, and heat-treatment is performed at 500 to 800°C.COPYRIGHT: (C)2016,JPO&INPIT【課題】少ない服用量でありながら除去すべき毒素の吸着容量及び選択吸着性に優れ、経済的かつ環境負荷を抑えた経口投与用の医薬用吸着剤の製造方法を提供する。【解決手段】平均細孔直径を1.5~2.2nm、BET比表面積を700~3000m2/g、平均粒径を100~1100μm、表面酸化物量を0.05meq/g以上、及び充填密度を0.4~0.8g/mLとする球状活性炭の製造に際し、ビスコース溶液を酸性の凝固浴中に導入して前記ビスコース溶液の凝固を通じてセルロースへの再生を促し前記凝固浴中にて球状の再生セルロースを得て、球状の再生セルロースを窒素雰囲気下300~700℃で炭化し、750~1000℃で水蒸気賦活を行い、酸洗浄して500~800℃で熱処理する。【選択図】なし
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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