USE OF CHIMERIC ANTIGEN RECEPTOR-MODIFIED T CELLS TO TREAT CANCER

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专利权人:

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

发明人:

JUNE, CARL, H,LEVINE, BRUCE, L,PORTER, DAVID, L,KALOS, MICHAEL, D,MILONE, MICHAEL, C

申请号：

TN2013000246

公开号：

TN2013000246A1

申请日:

2013.06.07

申请国别(地区):

TN

年份:

2014

代理人:

摘要：

The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/