Cyril Y. Bowers,Gloria S. Tannenbaum,David H. Coy,Simon J. Hocart
申请号：
US12298826
公开号：
US08536120B2
申请日:
2007.04.30
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides novel compounds that have been demonstrated to be modulators of the ghrelin receptor (growth hormone secretagogue receptor, GHS-R1a and subtypes, iso forms and variants thereof). These compounds are useful as antagonists of the ghrelin receptor as well as inverse agonist, partial agonist or a combination of these activities as medicaments for treatment and prevention of a range of medical conditions including, but not limited to, metabolic and/or endocrine disorders, gastrointestinal disorders, cardiovascular disorders, obesity and obesity-associated disorders, diabetes, central nervous system disorders, genetic disorders, and hyperproliferative disorders.
