T CELL RECEPTORS

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专利权人:

Bent Karsten Jakobsen

发明人:

Bent Karsten Jakobsen,Nathaniel Ross Liddy

申请号：

US12850425

公开号：

US20120027739A1

申请日:

2010.08.04

申请国别(地区):

US

年份:

2012

代理人:

摘要：

A T cell receptor (TCR) having the property of binding to EVDPIGHLY HLA-A1 complex and comprising a specified wild type TCR which has specific mutations in the TCR alpha variable domain and/or the TCR beta variable domain to increase affinity. Such TCRs are useful for adoptive therapy.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/